Journal of Korean Society of Ultrasound in Medicine 2010;29(3): 147-151.
Langerhans Cell Histiocytosis Arising from the Mandible as Diagnosed by US-guided Core Biopsy.
Soo Jin Kim, Eun Kyung Kim, Min Kyung Lee
1Department of Radiology, Center of Thyroid Cancer, National Cancer Center, Gyeonggi-do, Korea.
2Department of Radiology, Research Institute of Radiological Science, Yonsei University Heath System, Seoul, Korea.
3Department of Internal Medicine, Eulji University College of Medicine, Eulji University Hospital, Daejeon, Korea.
  Published online: September 1, 2010.
Langerhans cell histiocytosis (LCH) is a clonal proliferative disorder of Langerhans cells. Although LCH is not considered a malignant disease, its appearance on radiographs may be similar to that of a malignant tumor. The diagnosis of LCH is usually made by a soft tissue biopsy, or by bone marrow aspiration or curettage. We present a patient with a mandibular mass confirmed to be LCH by US-guided core needle biopsy, and present a strategy for diagnosing localized LCH of the bone based on the usefulness and reliability of the percutaneous biopsy.
Keywords: Langerhans cell histiocytosis; Mandibular mass; Eosinophillic granuloma on mandible; US-guided core needle biopsy; Bone mass
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