Journal of Korean Society of Medical Ultrasound 2004;23(1): 23-29.
Small Thyroid Nodules: Ultrasonographic Differentiation between Benign and Malignant Lesions.
Seon Jeong Min, Dae Young Yoon, Chul Soon Choi, Kyoung Ja Lim, Jeung Hee Moon, Young Lan Seo, Sang Joon Park, Young Cheol Yoon, Eun Joo Yun, Ik Won Kang, Gyung Kyu Lee
1Department of Radiology, Hallym University College of Medicine, Kangdong Seong-Sim Hospital, Korea.
2Department of Radiology, Hallym University College of Medicine, Hankang Seong-Sim Hospital, Korea.
  Published online: March 1, 2004.
PURPOSE: To evaluate the usefulness of ultrasonography in the differentiation between benignity and malignancy in the evaluation of small thyroid nodules (the longest diameter <10 mm). MATERIALS AND METHODS: Fine needle aspiration or surgery was performed for the evaluation of seventy two (44 benign and 28 malignant) small thyroid nodules from fifty eight patients. Ultrasonographic findings were retrospectively reviewed for the margin, echogenecity, presence of microcalcification, intranodular cystic change and peripheral hypoechoic halo. RESULTS: Ill-defined margin was more common in malignant nodules (61% vs 11%, p<0.05). In internal echogenecity, either iso- or hyperechogenicity was more coomon in benign nodules (45% vs 18%, p<0.05) while malignant nodules were often markedly hypoechoic (39% vs 18%, p<0.05). Malignant nodules contained more microcalcifications (36% vs 9%, p<0.05) whereas benign nodules often showed intranodular cystic change(39% vs 7%, p<0.05) and hypoechoic halo (41% vs 18%, p<0.05). CONCLUSION: Ultrasonography can be useful in the differentiation between benign and malignant small thyroid nodules.
Keywords: Thyroid, neoplasms; Thyroid, US
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