Journal of Korean Society of Medical Ultrasound 2002;21(2): 91-96.
Safety and Effectiveness of Percutaneous Biopsy of Focal Splenic Lesions under Ultrasonographic Guidance.
Hyun Young Han, Joo Heon Kim, Kyung Sook Shin
1Department of Diagnostic Radiology, Eulji University School of Medicine, Korea.
2Department of Anatomical Pathology, Eulji University School of Medicine, Korea.
3Department of Diagnostic Radiology, Chungnam National University, Korea.
  Published online: June 1, 2002.
PURPOSE: To evaluate the diagnostic yield and safety of ultrasound (US)-guided percutaneous needle biopsy for the diagnosis of focal splenic lesions. MATERIALS and METHODS: US guided, automated needle biopsy using an 18-gauge cutting needle was performed in 11 patients, consisted of nine men and two women (mean age = 49 years), with focal splenic lesions detected on the CT or US. Six patients (55%) had multiple lesions while five (45%) had a single lesion. Two of eleven patients had splenomegaly. None of 11 patients had the prior diagnosis of extrasplenic or hematopoietic malignancies. The biopsy was considered successful if a specific pathological diagnosis was possible. The diagnostic yield and frequency of complication were retrospectively analysed. RESULTS: Tissue adequate for histological diagnosis was obtained in nine (82%) of 11 patients, and no complications other than mild, localized discomfort occurred. Multifocal splenic lesions without splenomegaly in five patients were confirmed as Hodgkin's disease (n=2), tuberculosis (n=1), infarction (n=1), and hemangioma (n=1). All single lesion in four patients were proven as benign conditions including hamartoma (n=2), lymphangioma (n=1) and chronic organizing abscess (n=1), and only one of them with a large hamartoma received splenectomy while others did not receive further treatment. Although in two (18%) patients with multiple lesions and splenomegaly, no specific diagnosis was established by US-guided biopsy, malignant lymphoma and Hodgkin's disease were confirmed by surgery. CONCLUSION: US-guided automated needle biopsy is a safe and valuable procedure that can provides a specific diagnosis in patients with splenic lesions.
Keywords: Spleen, US; Spleen, biopsy; Biopsies, technology
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